CAS:1485081-57-9|Belinostat Amide

Catalogue Number:B131480
Chemical Name:Belinostat Amide
Synonyms:(2E)-3-[3-[(Phenylamino)sulfonyl]phenyl]-2-propenamide
CAS Number:1485081-57-9
Molecular Formula:C₁₅H₁₄N₂O₃S
Appearance:White to Off-White Solid
Melting Point:>68°C (dec.)
Molecular Weight:302.35
Storage:4°C, Inert atmosphere, Light sensitive
Solubility:Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Belinostat Amide is a metabolite of Belinostat (B131400), a novel histone deacetylase 3 selective inhibitor, which protects the b cells from cytokine-induced apoptosis.
References:Chou, D.H., et al.: Chem. Biol., 19, 669 (2012); Hwang, J.J., et al.: Inves. New. Drugs., 30, 1434 (2012); Dizon, D.S., et al.: Gynecol. Oncol., 125, 367 (2012);
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