CAS:15942-08-2|Ambroxol Cyclic Impurity Hydrochloride

Catalogue Number:A575910
Chemical Name:Ambroxol Cyclic Impurity Hydrochloride
Synonyms:trans-4-(6,8-Dibromo-1,4-dihydro-3(2H)-quinazolinyl)cyclohexanol Hydrochloride; NA 873 Hydrochloride; Ambroxol EP Impurity B Hydrochloride;
Impurity:Ambroxol EP Impurity B Hydrochloride
CAS Number:15942-08-2
Alternate CAS #
monohydrochloride: 15942-08-2
Molecular Formula:C₁₄H₁₉Br₂ClN₂O
Appearance:White to Off-White Solid
Melting Point:222 – 225°C
Molecular Weight:426.57
Storage:4°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).
References:Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);
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