CAS:161024-53-9|(R)-1-Acetyl-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carbonitrile

Catalogue Number:A539025
Chemical Name:(R)-1-Acetyl-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carbonitrile
Synonyms:1-Acetyl-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile;
CAS Number:161024-53-9
Molecular Formula:C₂₅H₂₈F₃N₃O₂
Molecular Weight:459.51
Category:Building Blocks; Chiral Molecules; Miscellaneous;
Applications:(R)-1-Acetyl-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carbonitrile is an intermediate in the synthesis of Deshydroxypropyl Silodosin (D290495) which is a metabolite of Silodosin (S465000); an α1a-adrenoceptor antagonist. Also used in the treatment of benign prostatic hypertrophy.
References:Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995); Murata, S., et al.: J. Urol., 164, 578 (2000)
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