CAS:1616493-44-7|Chidamide

Catalogue Number:C291980
Chemical Name:Chidamide
Synonyms:N-(2-Amino-4-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]-benzamide; N-(2-Amino-4-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide; CS 055; Chidamide; Epidaza;
CAS Number:1616493-44-7
Alternate CAS #
743438-44-0
Molecular Formula:C₂₂H₁₉FN₄O₂
Molecular Weight:390.41
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Chidamide is a newly designed histone deacetylase inhibitor that induces an antitumor effect in various cancer by increasing the acetylation levels of histone H3 and decrease histone deacetylase (HDAC) activity, induces apoptosis. Also, it is a potential utility of Chidamide for the treatment of Myelodysplastic syndromes.
References:Liu, Z., et al.: Biomed. Pharmacother., 83, 1032-1027 (2016)
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