CAS:1638286-64-2|De-boc Cabazitaxel

Catalogue Number:D206000
Chemical Name:De-boc Cabazitaxel
CAS Number:1638286-64-2
Molecular Formula:C₄₀H₄₉NO₁₂
Appearance:White Solid
Melting Point:>103°C (dec.)
Molecular Weight:735.82
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Semi-Synthetic;
Applications:De-Boc Cabazitaxel is an impurity of Cabazitaxel (C046500) which is a novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer.
References:Agarwal, N. et al.: Fut. Oncol., 7, 15 (2011); Mita, A. et al.: Clin. Cancer Res., 15, 723 (2009); Figg, W.D. et al.: Cancer Biol. Ther., 10, 1233 (2010);
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