CAS:1638785-17-7|4-(2-Chloroethyl)-N-methoxy-N,a,a-trimethyl-benzeneacetamide

Catalogue Number:C363650
Chemical Name:4-(2-Chloroethyl)-N-methoxy-N,a,a-trimethyl-benzeneacetamide
Synonyms:2-(4-(3-Chloropropanoyl)phenyl)-N-methoxy-N,2-dimethylpropanamide
CAS Number:1638785-17-7
Molecular Formula:C₁₄H₂₀ClNO₂
Appearance:White to Off-White Low-Melting Solid
Melting Point:35 – 40°C
Molecular Weight:269.77
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-(2-Chloroethyl)-N-methoxy-N,a,a-trimethyl-benzeneacetamide is an impurity of Bilastine (B385000), which is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.
References:Van Cauwenberge, P., et al.: Clin. Exp. Allergy, 30, 891 (2000), Bauchau, V., et al.: Eur. Respir. J., 24, 758 (2004), Lehman, J., et al.: Drugs, 66, 2309 (2006),
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