CAS:1640972-02-6|6-Chloro-N-methyl Piperidinyl 4-Pyrimidinamine

Catalogue Number:C593925
Chemical Name:6-Chloro-N-methyl Piperidinyl 4-Pyrimidinamine
Synonyms:6-Chloro-N-methyl-N-[(3R,4R)-4-methyl-1-(phenylmethyl)-3-piperidinyl]-4-pyrimidinamine
CAS Number:1640972-02-6
Molecular Formula:C₁₈H₂₃ClN₄
Appearance:Pale yellow oil
Molecular Weight:330.86
Storage:-20°C
Solubility:Dichloromethane
Category:Building Blocks; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-Chloro-N-methyl Piperidinyl 4-Pyrimidinamine is an intermediate in the synthesis of (3R,4R)-3-[(6-Amino-4-pyrimidinyl)methylamino]-4-methyl-b-oxo-1-piperidinepropanenitrile (A593950), a reagent used in the structural activity relationship studies on Tofacitinib bioisosteres.
References:Gehringer, M., et al.: ChemMedChem, 9, 2516 (2014)
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