CAS:166518-60-1|Avasimibe

Catalogue Number:A794680
Chemical Name:Avasimibe
Synonyms:CI 1011; PD 148515; N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-2-sulfamic Acid 6-Bis(1-methylethyl)phenyl Ester;
CAS Number:166518-60-1
Molecular Formula:C₂₉H₄₃NO₄S
Appearance:White Solid
Melting Point:173-175°C
Molecular Weight:501.72
Storage:-20°C
Solubility:DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Avasimibe is a selective inhibitor of Cholesterol Acyltransferase 1 and CYP2C9. Avasimibe is known to induce apoptosis of glioma cell lines as a model of glioblastoma.
References:Bemlih, S., et al.: Cancer. BIol. Therap., 9, 1025 (2010); Fahmi, O.A., et al.: Drug. Meta. Disp. 38, 1605 (2010);
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