CAS:168834-43-3|2-Amino-5-chloro-a-(2-cyclopropylethynyl)-a-(trifluoromethyl)benzenemethanol

Catalogue Number:A603285
Chemical Name:2-Amino-5-chloro-a-(2-cyclopropylethynyl)-a-(trifluoromethyl)benzenemethanol
Synonyms:2-Amino-5-chloro-α-(cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol
CAS Number:168834-43-3
Molecular Formula:C₁₃H₁₁ClF₃NO
Appearance:White to Off-White Solid
Melting Point:151-153°C
Molecular Weight:289.68
Storage:4°C
Solubility:Chloroform, Ethyl Acetate, Methanol
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Amino-5-chloro-a-(2-cyclopropylethynyl)-a-(trifluoromethyl)benzenemethanol is an impurity of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor.
References:Jiang, B., et al.: Tetrahedron. Lett., 43, 8323 (2002);
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