CAS:16974-42-8|Deoxysotalol

Catalogue Number:D245550
Chemical Name:Deoxysotalol
Synonyms:Sotalol Impurity A;
Impurity:Sotalol Impurity A
CAS Number:16974-42-8
Molecular Formula:C₁₂H₂₀N₂O₂S
Appearance:Off-White Solid
Melting Point:153-155°C
Molecular Weight:256.36
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly, Heated), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Deoxysotalol is the metabolite of Sotalol (S677300), a potent a-adrenergic receptor antagonist and A class III antiarrythmic. Several studies have examined deoxysotalol on its effects on prostaglandin (PGF2a and 15-methyl PGF2a)-evoked contraction using isolated rat uterus and also in potentiating the contractile effects of Oxytocin (O878500).
References:Uloth, et al.: J. Med. Chem., 9, 88 (1966); Narendranath, K.A., et al.: Euro. J. Pharmacol., 46, 15 (1977); Gautam, C.S., et al., Indian. J. Med. Rsch., 76, 107 (1982);
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