CAS:170713-71-0|Aureusimine B

Catalogue Number:A794570
Chemical Name:Aureusimine B
Synonyms:3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; Phevalin;
CAS Number:170713-71-0
Molecular Formula:C₁₄H₁₆N₂O
Appearance:Off-White to Light Grey Solid
Melting Point:179-181°C
Molecular Weight:228.29
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Aureusimine B is a novel small molecule isolated from S. aureus as one of a pair of related metabolites controversially identified as virulence factors in the pathology of Golden Staph. Aureusimine B has also been reported as an inhibitor of the protease, calpain.
References:Archer, G., et al.: Clin. Infect. Dis., 26, 1179 (1998); Novick, R., et al.: Mol. Microbiol., 48, 1429 (2003); Liang, X., et al.: Infect. Immun., 74, 4655 (2006); Geiger, T., et al.: J. Bacteriol., 190, 3419 (2008);
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