CAS:177408-65-0|8-Amino-7-oxopelargonic Acid Hydrochloride

Catalogue Number:A618750
Chemical Name:8-Amino-7-oxopelargonic Acid Hydrochloride
Synonyms:AOP; (8S)-8-Amino-7-oxo-nonanoic Acid Hydrochloride
CAS Number:177408-65-0
Alternate CAS #
Free Base: 682799-71-9
Molecular Formula:C₉H₁₇NO₃ • HCl
Appearance:White to Beige Solid
Melting Point:127-131°C
Molecular Weight:187.24 + 36.46
Storage:-20°C
Solubility:Methanol (Slightly), Water (Slightly)
Category:Standards; Miscellaneous;
Applications:An intermediate in the synthesis of biotin. Pimeloyl-CoA is transformed into AOP in the presence of L-alanine by the enzyme AOP synthase. The catalytic mechanism of AOP synthase has been studied for the elucidation of inhibitors as potential antimicrobial agents.
References:Ohsugi, M., et al.: J. Nutr. Sci. Vitaminol., 34 (4), 343 (1985), Pearson, B.M., et al.: Lett. Appl. Microbiol., 10 (2), 89 (1990), Ploux, O., et al.: Biochem. J., 283, 327 (1992)
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