CAS:1798871-30-3|Centrinone

Catalogue Number:C256613
Chemical Name:Centrinone
Synonyms:2-[[2-Fluoro-4-[[(2-fluoro-3-nitrophenyl)methyl]sulfonyl]phenyl]thio]-5-methoxy-N-(5-methyl-1H-pyrazol-3-yl)-6-(4-morpholinyl)-4-pyrimidinamine
CAS Number:1798871-30-3
Molecular Formula:C₂₆H₂₅F₂N₇O₆S₂
Appearance:Off-White to Pale Brown Solid
Melting Point:>187°C (dec.)
Molecular Weight:633.65
Storage:-20°C
Solubility:Aqueous Base (Very Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:Centrinone is a reversible inhibitor of Polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole assembly.
References:Wong, Y., et al.: Science, 348, 1155 (2015);
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