CAS:18037-10-0|2,4-Bis(trimethylsilyl)cytosine

Catalogue Number:B101910
Chemical Name:2,4-Bis(trimethylsilyl)cytosine
Synonyms:2-(Trimethylsiloxy)-4-[(trimethylsilyl)amino]-pyrimidine; N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine; O,N-Bis(trimethylsilyl)cytosine;
CAS Number:18037-10-0
Molecular Formula:C₁₀H₂₁N₃OSi₂
Molecular Weight:255.46
Category:Building Blocks; Miscellaneous;
Applications:2,4-Bis(trimethylsilyl)cytosine is an intermediate used in the synthesis of 1’-Epi Gemcitabine Hydrochloride (E588510), which is an α-Anomer of Gemcitabine.
References:Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),
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