CAS:181528-64-3|Artemether Tetrahydrofuran Acetate

Catalogue Number:A777415
Chemical Name:Artemether Tetrahydrofuran Acetate
Synonyms:(3aS,4R,6aS,7R,8S,10R,10aR)-Octahydro-8-methoxy-4,7-dimethyl-2H,10H-furo[3,2-i][2]benzopyran-10-ol 10-Acetate, ; [3aS-(3aα,4α,6aα,7β,8β,10α,10aS*)]-Octahydro-8-methoxy-4,7-dimethyl-2H,10H-furo[3,2-i][2]benzopyran-10-ol Acetate; Artemether Ph. Int. Impurity C
Impurity:Artemether Ph. Int. Impurity C
CAS Number:181528-64-3
Molecular Formula:C₁₆H₂₆O₅
Appearance:White to Off-White Solid
Melting Point:97-100°C
Molecular Weight:298.37
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A metabolite of Artemether (A777400) and derivative of the antimalarial drug Artemisinin (A777500). Studies suggest that it may display neurotoxicity in animals due to its interaction with iron.
References:Smith, S.L. et al.: Neurotoxicology, 19, 557 (1998); Blum, W. et al.: J. Chrom. B Biomed. Sci. Appl., 710, 101 (1998);
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