CAS:185517-21-9|R-(-)-Arundic Acid

Catalogue Number:A779500
Chemical Name:R-(-)-Arundic Acid
Synonyms:(2R)-2-Propyloctanoic Acid; (2R)-2-Propyloctanoic Acid; (R)-(-)-2-Propyloctanoic Acid; Arundic Acid; Cereact; ONO 2506; ONO 2506PO; Proglia;
CAS Number:185517-21-9
Molecular Formula:C₁₁H₂₂O₂
Appearance:Clear Colorless to Clear Pale Yellow Oil
Molecular Weight:186.29
Storage:4°C
Solubility:Chloroform (Slightly), Ethanol (Slightly), Ethyl Acetate (Slightly)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:’An astrocyte modulating agent, in acute ischemic stroke. A therapeutic agent for the treatment of neurodegenerative diseases including Alzheimer”s disease and ParkinsonтАЩs disease. This compound has neuroprotective properties. Also used in Glaucoma Research. Inhibits secondary injury and improves motor function in rats with spinal cord injury (1). Inhibits the production and release of S100 protein from astrocytes. Stimulates the human GLAST ortholog, EAAT1, expression in human neuroglioblastoma cells (2).’
References:Hanada M, et al. 2014. J Neurol Sci. 15;337(1-2):186-92.
Yanagisawa M, et al. 2015. Cell Death Dis. 19;6:e1693
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