CAS:191744-13-5|BDP 37

Catalogue Number:B129500
Chemical Name:BDP 37
Synonyms:2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one; CX 614; LiD 37;
CAS Number:191744-13-5
Molecular Formula:C₁₃H₁₃NO₄
Appearance:White to Off-White Solid
Melting Point:149-151°C
Molecular Weight:247.25
Storage:4°C
Solubility:Chloroform, DMSO, Methanol
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:BDP 37 is a AMPA modulator that may exhibit therapeutic properties for treating Alzheimer’s disease, schizophrenia, and mild cognitive impairment (MCI) (1,2,3,4). It is also an ampakine drug that facilitates activation of glutamatergic AMPA receptors.
References:(1) Arai, A., et al.: J. Pharmacol. Exp. Ther., 278, 627 (1996)
(2) Marini, A., et al.: J. Biol. Chem., 273, 29394 (1998)
(3) Balkowiec, A., et al.: J. Neurosci., 22, 10399 (2002)
(4) Dicou, E., et al.: Brain Res., 970, 221 (2003)
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