CAS:195141-96-9|Docetaxel 2′-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether

Catalogue Number:D205065
Chemical Name:Docetaxel 2′-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether
Synonyms:(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid Ester;
CAS Number:195141-96-9
Molecular Formula:C₆₁H₉₅NO₁₄Si₃
Appearance:White Solid
Molecular Weight:1150.66
Storage:4°C, Inert atmosphere
Solubility:Chloroform
Category:Building Blocks; Standards; Chiral Molecules; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Docetaxel 2′-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether is an intermediate used in the synthesis of 2-Debenzoyl-2-pentenoyldocetaxel (D205050), which is a related compound of Docetaxel (D494420), a chemotherapy drug that exhibits anti-mitotic properties and used for treating various metastatic cancers.
References:Yokoyama, G., et al.: Int J Clin Oncol 10, 139 (2005); Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Taskcm is committed to providing cost-effective products that facilitate drug delivery with our customers.
Email:sales@ebclink.com