CAS:199734-71-9|2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide

Catalogue Number:D288235
Chemical Name:2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide
CAS Number:199734-71-9
Molecular Formula:C₁₀H₁₆N₂O₄S₃
Appearance:White to Off-White Solid
Melting Point:>212C (dec.)
Molecular Weight:324.44
Storage:4°C
Solubility:Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly), Ethyl Acetate
Category:Standards; Enzyme Activators and Inhibitors;
Applications:2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100).
References:Blacklock, T., et al.: J. Org. Chem., 58, 1672 (1993); Tempkin, O., et al.: Tetrahedron: Asym., 7, 2721 (1996)
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