CAS:20010-99-5|2-(Aminomethyl)pyrazine

Catalogue Number:A617440
Chemical Name:2-(Aminomethyl)pyrazine
Synonyms:(Aminomethyl)-pyrazine; Pyrazinemethanamine; NSC 105567; Pyrazin-2-ylmethanamine; [(Pyrazin-2-yl)methyl]amine
CAS Number:20010-99-5
Molecular Formula:C₅H₇N₃
Appearance:Light Yellow to Yellow Oil
Molecular Weight:109.13
Storage:4°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:2-(Aminomethyl)pyrazine is a useful synthetic intermediate. It is used to synthesize pyrazolo[4,3-c]pyridinediones as orally bioavailable NADPH oxidase isoform 4 inhibitors for the treatment of idiopathic pulmonary fibrosis. It is also used to prepare pyrazolyl-indoles with the abilities to induce T-cell kinase inhibition.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Laleu, B., et al.: J. Med. Chem., 53, 7715 (2010); Velankar, A., et al.: Bioorg. Med. Chem., 18, 4547 (2010)
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