Catalogue Number:A633385
Chemical Name:3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
Synonyms:(R)-3-Amino-N-((R)-4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)-4-(2,4,5-trifluorophenyl)butanamide
CAS Number:2072867-07-1
Molecular Formula:C₂₆H₂₃F₉N₆O₂
Appearance:White to Off-White Solid
Melting Point:>73°C (dec.)
Molecular Weight:622.49
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules;
Applications:3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
References:Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)
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CAS:2072867-07-1|3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
