Catalogue Number:A729715
Chemical Name:3-(Acetylamino)-2-[[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]amino]carbonyl]benzoic Acid (Apremilast Benzoic Acid)
Synonyms:Apremilast Hydrolysis Impurity-2
Impurity:Apremilast Hydrolysis Impurity-2
CAS Number:2096492-41-8
Molecular Formula:C₂₂H₂₆N₂O₈S
Appearance:Off-White to Pale Yellow Solid
Melting Point:>125°C (dec.)
Molecular Weight:478.52
Storage:-20°C
Solubility:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules;
Applications:(aS)-3-Ethoxy-4-methoxy-a-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-benzenemethanamine is an impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis.
References:Gan, E. et al.: BioDrugs, 27, 359 (2013); Pathan, E. et al.: Annal. Rheum. DIs., 72, 1475 (2013)
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CAS:2096492-41-8|3-(Acetylamino)-2-[[[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]amino]carbonyl]benzoic Acid (Apremilast Benzoic Acid)
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