CAS:210755-45-6|CP-471474

Catalogue Number:C781305
Chemical Name:CP-471474
Synonyms:2-[[[4-(4-Fluorophenoxy)phenyl]sulfonyl]amino]-N-hydroxy-2-methylpropanamide; CP 471474;
CAS Number:210755-45-6
Molecular Formula:C₁₆H₁₇FN₂O₅S
Appearance:White to Off-White Solid
Melting Point:135-137°C (dec.)
Molecular Weight:368.38
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A broad spectrum inhibitor of matrix metalloproteinases that attenuates early left ventricular dilation after experimental myocardial infarction in mice. Studies show that it also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models.
References:Lindsey, M.L. et al.: Circulation, 105, 753 (2002); Rohde, L.E. et al.: Circulation, 99, 3063 (1999); Selman, M. et al.: Chest, 123, 1633 (2003);
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