CAS:2172256-78-7|6-​Acetyl-​8-​cyclopentyl-​5-​methylpyrido[2,​3-​d]​pyrimidine-​2,​7(1H,​8H)​-​dione

Catalogue Number:A173633
Chemical Name:6-​Acetyl-​8-​cyclopentyl-​5-​methylpyrido[2,​3-​d]​pyrimidine-​2,​7(1H,​8H)​-​dione
Synonyms:Palbociclib Impurity;
Impurity:Palbociclib Impurity;
CAS Number:2172256-78-7
Molecular Formula:C₁₅H₁₇N₃O₃
Appearance:Light Beige to Brown Solid
Melting Point:>201°C (dec.)
Molecular Weight:287.31
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-​Acetyl-​8-​cyclopentyl-​5-​methylpyrido[2,​3-​d]​pyrimidine-​2,​7(1H,​8H)​-​dione is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer.
References:Finn, R., et al.: Breast Cancer Res., 11, 5 (2009);
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