CAS:221243-82-9|4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine

Catalogue Number:A603004
Chemical Name:4-Amino-1-tert-butyl-3-(1’-naphthyl)pyrazolo[3,4-d]pyrimidine
Synonyms:1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1-NA-PP1;
CAS Number:221243-82-9
Molecular Formula:C₁₉H₁₉N₅
Appearance:White to Off-White Solid
Melting Point:215-218°C
Molecular Weight:317.39
Storage:-20°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A highly potent (IC50=1.5nM) and uniquely specific tyrosine kinase inhibitor of a rationally engineered v-Src tyrosine kinase. It is a COVID19-related research product.
References:Bishop, A.C., et al.: J. Am. Chem. Soc., 121, 627 (1999), Davies, S., et al.: Biochem. J., 351, 95 (2000),
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