CAS:231278-84-5|5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde

Catalogue Number:C366385
Chemical Name:5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde
Synonyms:[5-[4-[4-[(3-Fluorobenzyl)oxy]-3-chloroanilino]-6-quinazolinyl]-2-furancarboxaldehyde;
CAS Number:231278-84-5
Molecular Formula:C₂₆H₁₇ClFN₃O₃
Appearance:Yellow to Dark Brown Solid
Melting Point:>181°C (dec.)
Molecular Weight:473.88
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Very Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Lapatinib intermediate.
References:Khanna, I., et al.: J. Med. Chem., 40, 1619 (1997), Liebowitz, S., et al.: Biochem. Pharmacol., 38, 399 (1989), Klapper, L., et al.: Adv. Cancer Res., 77, 25 (2000), Tiseo, M., et al.: Curr. Med. Chem., 4, 139 (2004), Wood, E., et al.: Cancer Res., 64, 6652 (2004),
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