CAS:23598-72-3|3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic Acid

Catalogue Number:C380210
Chemical Name:3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic Acid
Synonyms:Cloxacillin EP Impurity D
Impurity:Cloxacillin EP Impurity D
CAS Number:23598-72-3
Molecular Formula:C₁₁H₈ClNO₃
Appearance:White to Pale Brown Solid
Melting Point:>125°C (dec.)
Molecular Weight:237.64
Storage:-20°C
Solubility:DMSO (Slightly), Ethyl Acetate (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic Acid (Cloxacillin EP Impurity D) is used in the preparation of isoxazolecarboxamides as a class of TGR5 agonists. Also used in the preparation of b-lactamase inhibitors.
References:Perumal, S. et al.: Bioorg. Med. Chem., 16, 6987 (2008); Budzik, B. et al.: Bioorg. Med. Chem. Lett., 20, 1363 (2010);
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