CAS:2378463-76-2|Abiraterone N-Oxide

Catalogue Number:A108540
Chemical Name:Abiraterone N-Oxide
CAS Number:2378463-76-2
Molecular Formula:C₂₄H₃₁NO₂
Appearance:White to Off-White Solid
Melting Point:>240°C (dec.)
Molecular Weight:365.51
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:Abiraterone N-Oxide is a derivative of Abiraterone (A108490), a steroidal cytochrome P 450 17a-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References:Denis, L., et al.: Cancer, 72, 3888 (1993),
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