CAS:239463-85-5|5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-Dihydroxybutanedioate

Catalogue Number:A628255
Chemical Name:5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-Dihydroxybutanedioate
CAS Number:239463-85-5
Molecular Formula:C₂₆H₃₁N₃O₈
Appearance:Off-White to Pale Yellow Solid
Melting Point:> 180° C (dec.)
Molecular Weight:513.54
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-Dihydroxybutanedioate is an intermediate of Silodosin (S465000) which is an a1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy.
References:Wang, X., et al.: A process for the preparation of silodosin, Indian Patent 2013CH03274, Jan 30, 2015
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