CAS:246529-22-6|Aramchol

CAS:246529-22-6|Aramchol

Catalogue Number:A765150
Chemical Name:Aramchol
Synonyms:(3β,5β,7α,12α)-7,12-Dihydroxy-3-[(1-oxoeicosyl)amino]-cholan-24-oic Acid; (3β)-Arachidylamido-7α,12α-dihydroxy-5β-cholan-24-oic Acid; C20-FABAC
CAS Number:246529-22-6
Molecular Formula:C₄₄H₇₉NO₅
Appearance:White to Off-White Solid
Melting Point:109-113°C
Molecular Weight:702.1
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules; Lipids/Fatty Acids, Glycerol Derivatives;
Applications:Aramchol is a fatty acid conjugate that exhibits hypocholesterolemic effects. Studies have shown that aramchol suppresses the activity of stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.
References:Leikin-Frenkel, A., et al.: Arch Med Res. 41, 397 (2010); Gonen, A., et al.: Pathobiology 70, 215 (2003)
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