CAS:2484719-14-2|Abiraterone Ethyl Ether

Catalogue Number:A108525
Chemical Name:Abiraterone Ethyl Ether
Synonyms:3-((3S,8R,9S,10R,13S,14S)-3-ethoxy-10,13-Dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
CAS Number:2484719-14-2
Molecular Formula:C₂₆H₃₅NO
Appearance:White to Off-White Solid
Melting Point:106-108°C
Molecular Weight:377.56
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
Category:Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Abiraterone Ethyl Ether is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17a-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References:Denis, L., et al.: Cancer, 72, 3888 (1993);
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