Catalogue Number:D221720
Chemical Name:N-Des(-3′-oxopropanenitrile)-N-(methyl)benzene Tofacitinib N-Hydrosulfinylmethylbenzene
Synonyms:Tofacitinib Related Compound 25; N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-(p-tolylsulfinyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;
CAS Number:2504210-33-5
Molecular Formula:C₂₇H₃₁N₅OS
Molecular Weight:473.63
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:An impurity of Tofacitinib(C781351); as Janus kinase inhibitor for treatment of rheumatoid arthritis.
References:Sheiner, L., et al.: Clin. Pharmacol. Ther., 25, 358 (1979), Dayneka, N., et al.: J. Pharmacokin. Biopharm., 21, 457 (1993), Changelian, P., et al.: Science, 302, 875 (2003), Lee, H., et al.: Clin. Pharmacol. Ther., 73, 348 (2003), Hutmacher, M., et al.: J. Clin. Pharmacol., 47, 238 (2007),
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CAS:2504210-33-5|N-Des(-3′-oxopropanenitrile)-N-(methyl)benzene Tofacitinib N-Hydrosulfinylmethylbenzene
