CAS:259793-88-9|6-Bromo-3-hydroxypyrazine-2-carboxamide

Catalogue Number:B103355
Chemical Name:6-Bromo-3-hydroxypyrazine-2-carboxamide
Synonyms:Br-T-705; 6-Bromo-3,4-dihydro-3-oxo-2-pyrazinecarboxamide;
CAS Number:259793-88-9
Molecular Formula:C₅H₄BrN₃O₂
Appearance:Yellow Solid
Melting Point:190 – 193°C
Molecular Weight:218.01
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
Applications:6-Bromo-3-hydroxypyrazine-2-carboxamide is a building block related to Favipiravir(F103350). Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever.
References:Oestereich, L., et al.: Antiviral Res., 105, 17 (2014); Baranovich, T., et al.: J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014)
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