Catalogue Number:D231258
Chemical Name:(E)-O-Demethylroxithromycin
Synonyms:(9E)-9-[O-[(2-Hydroxyethoxy)methyl]oxime]erythromycin;
CAS Number:261172-58-1
Molecular Formula:C₄₀H₇₄N₂O₁₅
Molecular Weight:823.02
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:(E)-O-Demethylroxithromycin is derived from (9E)-Erythromycin A Oxime is a metabolite of Roxithromycin (R700850) in humans. It has anti-Helicobacter pylori activity.
References:Nam, G. et al.: Bioorg. Med. Chem. Lett., 16, 569 (2006); Zhong, D. et al.: Drug Metab. Dispos., 28, 552 (2000); Yamazaki, H. et al.: Drug. Metab. Dispos., 26, 1053 (1998)
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