CAS:2627-69-2|5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranoside

Catalogue Number:A611700
Chemical Name:5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranoside
Synonyms:5-Aminoimidazole-4-carboxamide-1-?-D-ribofuranoside; AICAR; Acadesine; 5-Amino-1-?-D-ribofuranosyl-1H-imidazole-4-carboxamide; 5-Amino-4-imidazolecarboxamide Riboside; Arasine; GP 1-110; NSC 105823;
CAS Number:2627-69-2
Molecular Formula:C₉H₁₄N₄O₅
Appearance:White to Brown Solid
Melting Point:205-207C (dec.)
Molecular Weight:258.23
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
References:Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)
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