CAS:27023-37-6|Chlorotrityl Chloride

Catalogue Number:C422263
Chemical Name:Chlorotrityl Chloride
Synonyms:1-Chloro-4-(chlorodiphenylmethyl)-benzene; 1,1′-[Chloro(4-chlorophenyl)methylene]bis-benzene; Chloro(p-chlorophenyl)diphenyl-methane; 1-Chloro-4-(chlorodiphenylmethyl)benzene; (p-Chlorophenyl)(diphenyl)methyl Chloride
CAS Number:27023-37-6
Molecular Formula:C₁₉H₁₄Cl₂
Appearance:Off-White to Pale Yellow Solid
Melting Point:86-88°C
Molecular Weight:313.22
Storage:4°C
Solubility:Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Met
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Chlorotrityl Chloride is an impurity in the synthesis of para-Clotrimazole Isomer (C587405). para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.
References:Buechel, K.H. et al.: Drugs Made Ger., 15, 79 (1972); Bachmann, K. et al.: Pharmacol. Res., 50, 237 (2004)
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