CAS:27652-89-7|4-Chlorophenyl-2-pyridinylmethanol

Catalogue Number:C379615
Chemical Name:4-Chlorophenyl-2-pyridinylmethanol
Synonyms:α-(p-Chlorophenyl)-2-pyridinemethanol; (p-Chlorophenyl)(2-pyridinyl)methanol; NSC 31264; NSC 47970
CAS Number:27652-89-7
Molecular Formula:C₁₂H₁₀ClNO
Appearance:Off-White to Grey Solid
Melting Point:77-79˚C
Molecular Weight:219.67
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:a-(4-Chlorophenyl)-2-pyridinemethanol is used as a reagent in the synthesis of Carbinoxamine (Maleate salt: C175920), a histamine H1 antagonist. a-(4-Chlorophenyl)-2-pyridinemethanol is also an intermediate in the synthesis of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity.
References:Ohashi, R., et al.: Drug Metab. Disp., 34, 793 (2006); Reddy, M., et al.: Orient. J. Chem., 23, 691 (2007); Schlichting, D.: J. Pharm. Sci., 51, 134 (1962)
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