CAS:28624-56-8|(+)-α-Methylbenzylamine (-)-2,2-Dimethylcyclopropanecarboxylate

Catalogue Number:D286245
Chemical Name:(+)-α-Methylbenzylamine (-)-2,2-Dimethylcyclopropanecarboxylate
CAS Number:28624-56-8
Alternate CAS #
28624-52-4 & 3886-69-9
Molecular Formula:C₆H₁₀O₂ • C₈H₁₁N
Molecular Weight:114.14 + 121.18
Category:Building Blocks; Chiral Molecules; Miscellaneous;
Applications:(+)-α-Methylbenzylamine (-)-2,2-Dimethylcyclopropanecarboxylate is an intermediate in the synthesis of (R,R)-Cilastatin (C441120), which is a derivative of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References:Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),
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