CAS:300802-28-2|CIL56

Catalogue Number:C433128
Chemical Name:CIL56
Synonyms:2,7-bis(piperidinosulfonyl)-9H-fluoren-9-one oxime; CA3
CAS Number:300802-28-2
Molecular Formula:C₂₃H₂₇N₃O₅S₂
Appearance:White to Off-White Solid
Melting Point:>258°C (dec.)
Molecular Weight:489.61
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:CIL56 inhibits YAP/Tead transcriptional activity. Has anti-tumour effects on oesophageal adenocarcinoma with therapeutic potential in combination with 5-FU. Involved in ferroptosis, mediated by iron-dependent ROS.
References:Dixon, Scott J., et al.: ACS Chemical Biology., 10, 1604 (2015); Shimada, Kenichi., et al.; Nature Chemical Biology., 12, 497 (2016)
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