CAS:3094-09-5|5’-Deoxy-5-fluorouridine

Catalogue Number:D235725
Chemical Name:5’-Deoxy-5-fluorouridine
Synonyms:5-Fluorodesoxyuridine; 5′-DFUR; 5′-dFUrd; Doxifluridine; Flutron; Furtulon; Ro 21-9738;
Impurity:USP Capecitabine Related Compound B
CAS Number:3094-09-5
Molecular Formula:C₉H₁₁FN₂O₅
Appearance:White Solid
Melting Point:185-187°C
Molecular Weight:246.19
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.
References:Ingle, J., et al.: Cancer, 67, 886 (1991); Harvey, J., et al.: J. Clin. Oncol., 17, 1474 (1999); Asai-Sato, M., et al.: Int. J. Cancer, 115, 539 (2005); Rastelli, F., et al.: Tumori, 94, 370 (2008);
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