CAS:3102-57-6|C2 Ceramide

Catalogue Number:C262500
Chemical Name:C2 Ceramide
Synonyms:N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; N-Acetyl-D-sphingosine; Acetyl Ceramide; N-Acetylsphingosine;
CAS Number:3102-57-6
Molecular Formula:C₂₀H₃₉NO₃
Appearance:White to Off-White Solid
Melting Point:87-89°C
Molecular Weight:341.53
Storage:-20°C
Solubility:Chloroform (Slightly)
Stability
Moisture Sensitive
Category:Standards; Enzyme Activators and Inhibitors; Lipids/Fatty Acids, Glycerol Derivatives;
Applications:A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.
References:Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009), Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009), Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009),
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