CAS:32780-65-7|5-(2-Amino-1-hydroxyethyl)-2-hydroxy-benzamide Hydrochloride

Catalogue Number:A611125
Chemical Name:5-(2-Amino-1-hydroxyethyl)-2-hydroxy-benzamide Hydrochloride
Synonyms:Labetalol EP Impurity D
Impurity:Labetalol EP Impurity D
CAS Number:32780-65-7
Alternate CAS #
Free Base: 68807-83-0
Molecular Formula:C₉H₁₂N₂O₃ • HCl
Appearance:Pale Orange to Pale Brown Solid
Melting Point:200 – 205°C
Molecular Weight:196.20 + 36.46
Storage:-20°C
Solubility:DMSO (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-(2-Amino-1-hydroxyethyl)-2-hydroxy-benzamide Hydrochloride is an impurity of Labetalol (L096495), a specific competitive antagonist at both a-and b-adrenergic receptor sites. Labetalol is used as an antihypertensive.
References:Sybertz, E.J. et al.: J. Pharmacol. Exp. Ther., 218, 435 (1981); Clifton, J.E. et al.: J. Med. Chem., 25, 670 (1982); Goa, K.L. et al.: Drugs, 37, 583 (1989);
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