CAS:328955-57-3|6-Amino-4-(trifluoromethyl)-2(1H)-quinolinone

CAS:328955-57-3|6-Amino-4-(trifluoromethyl)-2(1H)-quinolinone

Catalogue Number:A397660
Chemical Name:6-Amino-4-(trifluoromethyl)-2(1H)-quinolinone
Synonyms:6-Amino-4-(trifluoromethyl)quinolin-2(1H)-one
CAS Number:328955-57-3
Molecular Formula:C₁₀H₇F₃N₂O
Molecular Weight:228.17
Category:Building Blocks; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:6-Amino-4-(trifluoromethyl)-2(1H)-quinolinone is an intermediate in the synthesis of LGD-2226 (L397615), an orally active potent and selective androgen receptor modulator used in the treatment of muscle wasting and osteoporosis. Show to have an anabolic effect on muscle and bone tissue.
References:Miner, J. et al.: Endo. Soc., 148, 0793 (2006);
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