CAS:356568-70-2|Barbadin

Catalogue Number:B118250
Chemical Name:Barbadin
Synonyms:3-Amino-5-[4-(phenylmethyl)phenyl]thieno[2,3-d]pyrimidin-4(3H)-one
CAS Number:356568-70-2
Molecular Formula:C₁₉H₁₅N₃OS
Appearance:White to Pale Yellow Solid
Melting Point:175-180°C
Molecular Weight:333.41
Storage:4°C
Solubility:Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Sligh
Category:Standards; Enzyme Activators and Inhibitors;
Applications:Barbadin is a selective b-arrestin/b2-adaptin inhibitor. It selectively inhibits the interaction between b-arrestin and the b2-adaptin subunit of the clathrin adaptor protein AP2 without affecting the formation of receptor/b-arrestin complexes.
References:Beautrait, A., et al.: Nat Commun. 8, 15054 (2017)
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