CAS:36093-85-3|4-Aminodeoxopteroic Acid

Catalogue Number:A603895
Chemical Name:4-Aminodeoxopteroic Acid
Synonyms:4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoic Acid; 4-Amino-4-deoxopteroic Acid
CAS Number:36093-85-3
Molecular Formula:C₁₄H₁₃N₇O₂
Appearance:Yellow to Dark Brown Solid
Melting Point:>226°C (dec.)
Molecular Weight:311.3
Storage:-20°C
Solubility:DMSO (Slightly, Heated), Methaol (Slightly)
Category:Building Blocks; Amino Acids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Aminodeoxopteroic Acid, is an intermediate for the synthesis of Aminopterin (A628850), a folic acid antagonist. They can also be used as precursors for De Novo synthesis of antifolates: A novel class of antimalarials.
References:Matherly, L.H., et al.: Cancer Res., 45, 1073 (1985); Nduati, E., et al.: Anti. Age. Chem., 49, 3652 (2005);
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