CAS:36148-89-7|Amphotericin B Methyl Ester (>80%)

Catalogue Number:A634255
Chemical Name:Amphotericin B Methyl Ester (>80%)
Synonyms:Amphotericin B Monomethyl Ester;
CAS Number:36148-89-7
Molecular Formula:C₄₈H₇₅NO₁₇
Appearance:Dark Yellow to Dark Orange Solid
Melting Point:>118°C (dec.)
Molecular Weight:938.11
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Light Sensitive
Category:Standards; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:Amphotericin B Methyl Ester (>80%) is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B Methyl Esterin is a cholesterol binding compound that showed inhibiton of human immunodeficiency virus type 1 (HIV-1).
References:Waheed, A.A. et al.: J. Biol. Chem., 281, 28699 (2006); Waheed, A. et al.: J. Virol., 82, 9776 (2008); Waheed, A., et al.: J. Biol. Chem., 281, 28699 (2006)
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