CAS:389621-79-8|3-Amino-5-nitrophenylboronic Acid, Hydrochloride

CAS:389621-79-8|3-Amino-5-nitrophenylboronic Acid, Hydrochloride

Catalogue Number:A622723
Chemical Name:3-Amino-5-nitrophenylboronic Acid, Hydrochloride
CAS Number:389621-79-8
Alternate CAS #
Free Base: 89466-05-7
Molecular Formula:C₆H₇BN₂O₄ • HCl
Appearance:Pale Brown to Light Brown Solid
Melting Point:>228°C (dec.)
Molecular Weight:181.94 + 36.46
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
Applications:3-Amino-5-nitrophenylboronic Acid, HCl is a useful reagent for preparing heterocycle carboxamides as Bruton’s tyrosine kinase (Btk) inhibitors for treating immunological and oncological disorders.
References:Bonafoux, D., et al.: PCT Int. Appl. (2014), WO 2014210255 A1
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