CAS:402849-26-7|3-Chloroindomethacin

Catalogue Number:C367395
Chemical Name:3-Chloroindomethacin
Synonyms:[1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic Acid; 1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-acetic Acid; Indomethacin Impurity G; Indomethacin EP Impurity G
CAS Number:402849-26-7
Molecular Formula:C19H15Cl2NO4
Molecular Weight:392.23
Storage:-20°C
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-Chloroindomethacin (Indomethacin EP Impurity G) is an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO).
References:Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)
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