CAS:40371-51-5|(S)-(-)-4-Amino-2-hydroxybutyric Acid

Catalogue Number:A611245
Chemical Name:(S)-(-)-4-Amino-2-hydroxybutyric Acid
Synonyms:(2S)-4-Amino-2-hydroxybutanoic Acid; (S)-4-Amino-2-hydroxybutanoic Acid; (S)-4-Amino-2-hydroxybutyric Acid; 4-Amino-(2S)-hydroxybutyric Acid; L-(-)-4-Amino-2-hydroxybutyric Acid; L-(-)-γ-Amino-α-hydroxybutyric Acid; L-4-Amino-2-hydroxybutyric Acid; L-γ-Amino-α-hydroxybutyric Acid; Amikacin EP Impurity I
CAS Number:40371-51-5
Molecular Formula:C₄H₉NO₃
Appearance:White to Pale Beige Solid
Melting Point:194-195ºC
Molecular Weight:119.12
Storage:20°C, Hygroscopic
Solubility:Methanol (Very Slightly), Water (Soluble)
Stability
Hygroscopic
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(S)-(-)-4-Amino-2-hydroxybutyric Acid is an analogue of γ-aminobutyric acid (GABA) with potential inhibitory activity on GABA binding and uptake by brain. Injection of (S)-(-)-4-Amino-2-hydroxybutyric Acid showed no significant changes in plasma growth hormone (GH) in healthy patients but increased plasma GH, prolactin, and cortisol levels in cerebrovascular patients.
References:Honore, T. et al.: Eur. J. Med. Chem., 13, 429 (1978); Takahara, J. et al.: Horm. Metab. Res., 12, 31 (1980);
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