CAS:446-86-6|Azathioprine

Catalogue Number:A803350
Chemical Name:Azathioprine
Synonyms:6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine; BW-57-322; NSC-39084;
CAS Number:446-86-6
Molecular Formula:C₉H₇N₇O₂S
Appearance:Pale Yellow to Yellow Solid
Melting Point:>225°C (dec.)
Molecular Weight:277.26
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:An immunosuppressive antimetabolite. Also active as a disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects.
References:Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979), Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979), Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987), Sandborn, W.J., et al.: : Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998,)
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